Science in BIOANT laboratories
Published scientific paper in Nature
On Wednesday, December 22nd 2021, a palaeogenetic study entitled ‘Large-scale migration into Britain during the Middle to Late Bronze Age’ was published in Nature. Dr. Mario Novak, an employee of the Institute for Anthropological Research, is one of co-authors of this global study.
A copy of the article can be found here:
Published scientific paper in Molecules journal (Q1, IF 4.411 (2020))
Published scientific paper entitled “Amidine- and Amidoxime-Substituted Heterocycles: Synthesis, Antiproliferative Evaluations and DNA Binding” in scientific journal Molecules in which participated dr. Mirela Sedić from the Institute of Anthropology as a co-author.
Open Access via the following link:
Published two papers working on data in BIOANT laboratories
Working and data mining in our Centre for bioanthropology, two more scientific papers have emerged:
- Should We Embed in Chemistry? A Comparison of Unsupervised Transfer Learning with PCA, UMAP, and VAE on Molecular Fingerprints
- by authors: Mario Lovrić, Tomislav Đuričić, Han T. N. Tran, Hussain Hussain, Emanuel Lacić, Morten A. Rasmussen, Roman Kern (IF 8.071)
- Combining short-term bioassays using fish and crustacean model organisms with ToxCast in vitro data and broad-spectrum chemical analysis for environmental risk assessment of the river water (Sava, Croatia)
- by authors: Olga Malev, Sanja Babić, Anja Sima Cota, Draženka Stipaničev, Siniša Repec, Martina Drnić, Mario Lovrić, Krunoslav Bojanić, Sandra Radić Brkanac, Rozelindra Čož-Rakovac, Göran Klobučar (IF 5.863)
Scientific paper is published in IJMS
A scientific paper entitled “The Sphingosine Kinase 2 Inhibitor ABC294640 Restores the Sensitivity of BRAFV600E Mutant Colon Cancer Cells to Vemurafenib by Reducing AKT-Mediated Expression of Nucleophosmin and Translationally-Controlled Tumor Protein” was published in the International Journal of Molecular Sciences. Mirela Sedić, PhD, one of the authors of the paper, is from the Institute for Anthropological Research. This paper is the result of scientific research conducted within the project HRZZ IP-2018-01-3900 led by M. Sedić.
Access to paper via the following link: https://www.mdpi.com/1422-0067/22/19/10767/htm
Scientific paper in Nutrients journal
New paper published in Nutrients (IF5.717 (2020)) “Evaluation of the Food Choice Motives before and during the COVID-19 Pandemic: A Cross-Sectional Study of 1232 Adults from Croatia” by Ivan Dolanc, Antonija Jonjić, Eva Anđela Delale, Saša Missoni and Miran Čoklo from the Institute for anthropological research as coauthors to the research. The research was conducted as part of the international project CFC-CRO-BE (in cooperation with the Institute for Tropical Medicine, Antwerp, Belgium and the Psychiatric Hospital Ugljan, Croatia).
The paper is in Open access at https://www.mdpi.com/2072-6643/13/9/3165/htm
New paleogenetic study in PLOS ONE
On Wednesday, March 10th 2021, paleogenetic study of the victims of the Copper Age massacre from Potočani near Požega titled „Genome-wide analysis of nearly all the victims of a 6200 year old massacre“ was published in scientific journal PLOS ONE. Dr. Mario Novak and Dr. Ivor Janković from the Centre for Applied Bioanthropology of the Institute for Anthropological Research participated and co-authored the study. This study generated huge interest in Croatian and international media.
Published work based on CRIBS project in Nutrients journal
In July 2020, the international journal Nutrients (Q1, Impact factor 4,546) published a paper on the Mediterranean diet and lifestyle of pregnant women and the observed differences between the mainland and the island part of Dalmatia. The paper is based on the results of the Croatian Science Foundation’s scientific project “Cohort Study of Those Born in the Eastern Adriatic Islands (CRIBS)”, and the authors are associates from the Institute for Anthropological research (Saša Missoni, PhD; Dubravka Havaš Auguštin, PhD; Jelena Šarac,PhD; Natalija Novokmet, PhD and Nives Fuchs and colleagues from the Srebrnjak Children ‘s Hospital.
Dr.sc. Mario Novak published scientific paper in Science: ‘Origins and genetic legacy of prehistoric dogs’
Dr.sc. Mario Novak published a new article in Science: ‘Origins and genetic legacy of prehistoric dogs’
https://science.sciencemag.org/content/370/6516/557.full
Abstract
Dogs were the first domestic animal, but little is known about their population history and to what extent it was linked to humans. We sequenced 27 ancient dog genomes and found that all dogs share a common ancestry distinct from present-day wolves, with limited gene flow from wolves since domestication but substantial dog-to-wolf gene flow. By 11,000 years ago, at least five major ancestry lineages had diversified, demonstrating a deep genetic history of dogs during the Paleolithic. Coanalysis with human genomes reveals aspects of dog population history that mirror humans, including Levant-related ancestry in Africa and early agricultural Europe. Other aspects differ, including the impacts of steppe pastoralist expansions in West and East Eurasia and a near-complete turnover of Neolithic European dog ancestry.